RELION
======

|RELION| (for **RE**\ gularised **LI**\ kelihood **O**\ ptimisatio\ **N**\ , pronounce rely-on) is a software package that employs an empirical Bayesian approach for electron cryo-microscopy (cryo-EM) structure determination. 
It is developed in the group of `Sjors Scheres <https://www2.mrc-lmb.cam.ac.uk/groups/scheres/>`_ at the `MRC Laboratory of Molecular Biology <https://www2.mrc-lmb.cam.ac.uk>`_.

.. note::

    As the `cryo-EM resolution revolution <https://science.sciencemag.org/content/343/6178/1443.summary>`_ progresses, software protectionism is also on the rise.
    We are proud to distribute |RELION| under a *GPLv2* license.
    This means that anyone (including commercial users) can download, use and modify |RELION| for free.
    If |RELION| is useful in your work, please do make sure that our :doc:`Team <Team>` members are credited appropriately and cite `our papers <https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html>`_.

Table of Contents
-----------------

**These pages refer to RELION-5.0, which is now in public beta-testing.**
For documentation on the latest stable release of RELION-4.0, please see `here <https://relion.readthedocs.io/en/release-4.0/>`_. 

-   :doc:`Whats-new`
-   :doc:`Team`
-   :doc:`Installation`
-   :doc:`SPA_tutorial/index`
-   :doc:`STA_tutorial/index`
-   :doc:`Onthefly`
-   :doc:`Reference/index`

-   :ref:`search`

.. toctree::
    :maxdepth: 2
    :hidden:

    Whats-new
    Team
    Installation
    SPA_tutorial/index
    STA_tutorial/index
    Onthefly
    Reference/index